Which is stronger bactrim or clindamycin

Williams and Creech say this study is a preliminary first step since it takes a long time to do the prospective research that will change the standard of care. Vanderbilt is participating in such a trial. Vanderbilt University. Close Menu Vanderbilt University.

Research News All Vanderbilt. The only drawback is the risk of hemolysis to patients with G6PD deficiency which is slightly more prevalent here. What i would like to point out as a microbiologist we must always think the most common pathogen causing the skin infection. So co-trimoxazole is ok as a primary drug for skin infections.

Clindamycin on the other hand must be reserved in case of MRSA isolate resistant to co-trimoxazole. I just wonder…. I had read about this study last week and it basically confirmed what I normally do in practice for patients who fit the study group profile.

I tend to avoid clindamycin because of the diarrhea side effect. She was not happy that I insisted on seeing the rash. No S-J Syndrome, thank goodness.

But she sure was miserable for a few days. Clindamycin is most certainly NOT cheap. Hence, they are not equivalents. The treatment for MRSA boils or abscesses is drainage and, in most cases antibiotics add nothing. No wonder the two drugs are the same!! I agree with others that the Miller et al.

I would also hope that the Miller group and others will replicate and extend this investigation. I think it would be important to add a placebo arm to obtain data on treatment-free remission. In addition, topical treatments, such as clindamycin gel and mupirocin, appear to be effective in some cases, and I think it might be important to study topical vs.

Wrong antibiotic used for resistant skin infections. August 18, Clindamycin versus trimethoprim-sulfamethoxazole for uncomplicated skin infections. N Engl J Med. Miller and colleagues conducted their study in adults as well as children. Patients were included if they had either a discrete skin abscess or cellulitis, or both. They were excluded if they had one of the following:. Details of the trial All discrete abscesses were incised and drained, and patients were randomly assigned to either:.

The study enrolled patients— in the clindamycin group and in the trimethoprim-sulfamethoxazole group. One hundred sixty patients An incision and drainage procedure was performed in The most common organism isolated was S aureus of patients, or